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Writer's pictureDr. Gaffud

Feline Cancer: Types, Causes, Treatment, and Holistic Care


Sleeping tabby cat on wooden floor with sad and weak expression.


What is Feline Cancer?

An orange cat peeks from behind a cardboard with inquisitive mood.

Feline cancer, also known as cat cancer or cat neoplasms, is a group of diseases characterized by the uncontrolled growth of abnormal cells. These cells form tumors or spread throughout the body, disrupting normal organ function. 


“Feline cancer refers to various types of malignant tumors that affect domestic cats, similar to cancers found in humans. It is a significant cause of morbidity and mortality in cats, with common types including lymphoma, squamous cell carcinoma, sarcoma, and mammary tumors,” (Ludwig, L., et al., 2022; Giugliano, R., et al., 2024; Jessica, L., et al., 2020).”

Although less common in cats than dogs, cancers in cats are often aggressive and challenging to detect early due to the subtle nature of their symptoms. Early diagnosis and a proactive approach to treatment are key to managing this condition effectively.


How Common is Feline Cancer?


Cancer is a leading cause of death in cats, with increasing rates observed in recent years (Giugliano, R., et al., 2024). In a South African study, 0.78% of feline admissions were due to cancer (Zambelli, A., 2015).


What are the Different Types of Feline Cancer?

Siamese cat with blue eyes wearing a collar, looking up. Background is green and blurry.

Several types of feline cancer affect cats, each with unique characteristics and treatment challenges. The common types of feline cancer are listed below.


  • Lymphoma: A cancer of the lymphatic system,  with alimentary and mediastinal forms being the most common. Retroviral infections, such as FeLV and FIV, are significant risk factors for lymphoma, particularly in younger cats (Leite-Filho, R., et al., 2020; Kokkinaki, K., et al., 2021; Court, E., et al., 1997). 

  • Squamous Cell Carcinoma (SCC): A form of skin or oral cancer typically develops in areas exposed to sunlight or in the mouth. It is particularly common in light-colored cats. The study of Santos, A., et al. (2023) concluded that “The prevalence of metastatic SCCs in cats was 5.3% (9/169), with metastases affecting lymph nodes in 66% (6/9) of cats.

  • Mammary Gland Tumors: Cancer of the mammary glands, often malignant. These tumors are more frequent in unspayed female cats, but early spaying significantly reduces the risk.

  • Fibrosarcoma: A type of cancer arising in connective tissues, sometimes associated with injection sites. It grows aggressively and requires early treatment.

  • Mast Cell Tumors: Tumors formed from mast cells, which are part of the immune system. They appear on the skin or in internal organs, such as the spleen.

  • Osteosarcoma: A rare but aggressive bone cancer that often requires amputation of the affected limb followed by chemotherapy.

  • Hemangiosarcoma: A cancer of the blood vessel walls, typically found in organs like the liver or spleen. It is highly aggressive and often spreads quickly.


Each type of cancer has unique characteristics, symptoms, and treatment approaches. Early diagnosis is essential for effective management.


What are the Symptoms That a Cat Has Cancer?

Orange cat with calm mood lying on a laptop on a beige couch.

The symptoms of feline cancer vary depending on the type and location of the disease. Common signs to watch for are listed below.


  • Presence of a Mass: Some cats with cancer present with an obvious mass lesion while others don’t. Often, tumors are relatively advanced when detected, making management more challenging (Blackwood, L., 2013).

  • Lymphadenopathy: Regional lymphadenopathy, or swollen lymph nodes, is common in cats with cancer. This symptom sometimes mimics other conditions, such as cat scratch disease, which also presents with lymphadenopathy but typically without systemic symptoms (Dhal, U., et al., 2021).

  • General Signs of Illness: While not specific to cancer, general signs such as weight loss, lethargy, and decreased appetite are indicative of an underlying malignancy  (Blackwood, L., 2013).

  • Stress and Behavioral Changes: Most cats exhibit stress or behavioral changes, especially during clinic visits, which complicate diagnosis and treatment decisions (Blackwood, L., 2013).


While the presence of a mass and regional lymphadenopathy are common indicators of cancer in cats, other general signs of illness and behavioral changes can also be present. Early detection is often tricky, as tumors may be advanced by the time they are noticed. Regular veterinary check-ups are crucial for early diagnosis and management.


How is Cancer in Cats Diagnosed?

Vet using ultrasound probe on cat's belly in clinical setting. Cat licks nose with calm tone.

Diagnosing cancer in cats involves a combination of different techniques.


  • Physical Exam: Veterinarians assess for abnormal lumps, changes in weight, or other signs of illness.

  • Imaging: X-rays, ultrasounds, and advanced scans like CT or MRI help visualize tumors and their spread.

  • Bloodwork: Routine tests detect organ dysfunction or anomalies indicative of cancer.

  • Biopsy or Fine Needle Aspiration: Tissue or cell samples are analyzed to confirm the presence and type of cancer.


Prompt and accurate diagnosis is essential for tailoring an effective treatment plan.


What are the Treatment Options for Feline Cancer?

Vet in blue scrubs wearing gloves holds ginger cat.

Treatment for feline cancer depends on the cat’s type, stage, and overall health. Standard options are listed below.


  • Surgery: Often used to remove localized tumors, surgery is most effective when the cancer has not spread.

  • Chemotherapy: Tailored to cats, chemotherapy manages systemic cancers like lymphoma with minimal side effects.

  • Radiation Therapy: Targets specific tumors, mainly when surgery isn’t feasible.

  • Palliative Care: Focused on comfort and quality of life, palliative care includes pain management and supportive therapies for advanced cases.


A multimodal approach combining these treatments often provides the best outcomes, and the veterinarian works closely with pet owners to determine the most suitable plan.


Holistic Care for Cats with Cancer

A fluffy cat receiving acupuncture; a hand holds a needle near its fur.

Holistic care for cats with cancer involves a comprehensive approach that considers the medical treatment of the disease and the ethical, emotional, and practical aspects of care (Wong, R., et al., 2001; Moore, A., 2011). This approach is essential due to the unique challenges and considerations in treating feline cancer patients. The key components are listed below.


  • Nutritional Management: High-quality, protein-rich diets with limited carbohydrates support immune function and energy levels.

  • Supplements: Omega-3 fatty acids, antioxidants, and other supplements bolster the body’s defenses.

  • Stress Reduction: Providing a calm, enriched environment with plenty of affection and stimulation helps reduce anxiety and improves the cat’s emotional health.

  • Integrative Therapies: Treatments like acupuncture and herbal medicine, under the guidance of a veterinarian, help manage pain and inflammation.


Holistic care focuses on treating the whole cat—physically, emotionally, and mentally—ensuring a better quality of life during and after treatment.


Feline cancer is a serious but manageable condition with the right approach to diagnosis, treatment, and care. Whether pursuing traditional therapies, holistic strategies, or a combination, pet owners play a vital role in their cat's journey. Always consult a trusted veterinarian to develop a personalized care plan tailored to the cat’s needs.


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